{"id":6659,"date":"2025-12-04T10:52:45","date_gmt":"2025-12-04T08:52:45","guid":{"rendered":"https:\/\/dev.amhes.com\/proionta\/thermogen\/"},"modified":"2026-04-20T11:14:11","modified_gmt":"2026-04-20T08:14:11","slug":"thermogen","status":"publish","type":"product","link":"https:\/\/amhes.com\/en\/proionta\/thermogen\/","title":{"rendered":"Thermogen"},"content":{"rendered":"<h3 style=\"text-align: center;\"><em><strong>AVAILABLE FOR SHIPMENT FROM MARCH 23<\/strong><\/em><\/h3>\n<p><strong>LOSEBiG THERMOGEN<\/strong><\/p>\n<p><strong>The Science of Metabolic Activation<\/strong><\/p>\n<p>Metabolism isn't just about calorie numbers. It's about rate, adaptability, and the body's ability to convert energy into movement and fuel burn. When metabolic pathways are working correctly, the body doesn't store; it uses. It doesn't hold on; it consumes.<\/p>\n<p>The <strong>LOSEBiG THERMOGEN<\/strong> it is a scientifically designed formula for thermogenic and metabolic support, based on herbal extracts, bioactive polyphenols, and micronutrients that act synergistically for:<\/p>\n<ul>\n<li>activation of metabolic mechanisms,<\/li>\n<li>increase in energy expenditure,<\/li>\n<li>fat burning support,<\/li>\n<li>better blood sugar and appetite control.<\/li>\n<\/ul>\n<p><strong>The Formula That Works With Your Body<\/strong><\/p>\n<ul>\n<li><strong>Metabolaid\u00ae Complex (Lemon Verbena &amp; Hibiscus) \u2013 500 mg<\/strong><br \/>\nPatented botanical complex studied for its action in activating AMPK, the cell's key \u201cenergy sensor.\u201d Supports increased energy expenditure, reduced fat mass, and appetite regulation.<\/li>\n<li><strong>Apple Cider Vinegar - 450 mg<\/strong><br \/>\nIt contributes to the feeling of satiety and postpartum glucose regulation, helping the body avoid insulin spikes that lead to fat storage.<\/li>\n<li><strong>Soy Lecithin \u2013 390 mg<\/strong><br \/>\nSource of phospholipids involved in lipid transport, cell membrane structure, and fatty acid metabolic flow.<\/li>\n<li><strong>Green Tea Extract (50% EGCG) \u2013 180 mg<\/strong><br \/>\nThe catechins in green tea enhance fatty acid oxidation and thermogenesis, increasing energy expenditure at rest and during exercise.<\/li>\n<li><strong>Zinc Picolinate \u2013 9 mg<\/strong><br \/>\nZinc contributes to normal macronutrient metabolism and the regulation of hormones related to appetite and energy.<\/li>\n<li><strong>Cayenne Pepper \u2013 15 mg<\/strong><br \/>\nCapsaicin mildly increases thermogenesis and energy expenditure by activating calorie-burning mechanisms.<\/li>\n<li><strong>Berberis aristata (85% Berberine) \u2013 30 mg<\/strong><br \/>\nBerberine supports glucose and lipid regulation, activates AMPK, and contributes to improved metabolic response.<\/li>\n<li><strong>White Mulberry Leaf Extract \u2013 150 mg<\/strong><br \/>\nIt reduces the absorption of carbohydrates from the intestine and contributes to blood sugar stabilization, limiting lipogenesis.<\/li>\n<\/ul>\n<p><strong>The Science of Synergy<\/strong><\/p>\n<p>LOSEBiG THERMOGEN doesn't target a single pathway but a complete metabolic system:<\/p>\n<ul>\n<li><strong>Metabolism activation<\/strong> through AMPK (Metabolaid\u00ae, Berberine, EGCG).<br \/>\n\u2022 <strong>Thermogenesis increase<\/strong> with capsaicin and green tea polyphenols.<br \/>\n\u2022 <strong>Improvement of fatty acid burning<\/strong> through phospholipids and catechins.<br \/>\n\u2022 <strong>Sugar &amp; appetite regulation<\/strong> with apple cider vinegar and white mulberry.<br \/>\n\u2022 <strong>Stable metabolic performance<\/strong> without stimulants and caffeine.<\/li>\n<\/ul>\n<p><strong>Daily Dosage &amp; How to Use<\/strong><\/p>\n<ul>\n<li><strong>Dose:<\/strong> 3 capsules daily<br \/>\n\u2022 <strong>Download<\/strong> 1 capsule in the morning, 1 capsule in the early afternoon, and 1 capsule in the evening with water<br \/>\n\u2022 <strong>Duration<\/strong> Daily use or 12-week cycles<br \/>\n\u2022 <strong>Appropriate<\/strong> For long-term metabolic support without nervous stimulation<\/li>\n<\/ul>\n<p><strong>Composition &amp; Action Chart - LOSEBiG THERMOGEN<\/strong><\/p>\n<table>\n<thead>\n<tr>\n<td><strong>Ingredient<\/strong><\/td>\n<td><strong>Concentration \/ dose<\/strong><\/td>\n<td><strong>Main Ingredients<\/strong><\/td>\n<td><strong>Evidence-based Action<\/strong><\/td>\n<\/tr>\n<\/thead>\n<tbody>\n<tr>\n<td>Metabolaid\u00ae<\/td>\n<td>500 milligrams<\/td>\n<td>Polyphenols verbena &amp; hibiscus<\/td>\n<td>AMPK activation, reduction of fat mass<\/td>\n<\/tr>\n<tr>\n<td>Apple Cider Vinegar<\/td>\n<td>450 mg<\/td>\n<td>Acetic acid<\/td>\n<td>Saturation, blood sugar regulation<\/td>\n<\/tr>\n<tr>\n<td>Soy Lecithin<\/td>\n<td>390 mg<\/td>\n<td>Phospholipids<\/td>\n<td>Lipid metabolism<\/td>\n<\/tr>\n<tr>\n<td>Green Tea Extract<\/td>\n<td>180 mg<\/td>\n<td>EGCG 50%<\/td>\n<td>Thermogenesis, fat oxidation<\/td>\n<\/tr>\n<tr>\n<td>Zinc Picolinate<\/td>\n<td>9 mg<\/td>\n<td>Zinc<\/td>\n<td>Energy metabolism<\/td>\n<\/tr>\n<tr>\n<td>Cayenne Pepper<\/td>\n<td>15 mg<\/td>\n<td>Capsaicin<\/td>\n<td>Increase in energy expenditure<\/td>\n<\/tr>\n<tr>\n<td>Berberis aristata<\/td>\n<td>30 mg<\/td>\n<td>Verberin 85%<\/td>\n<td>AMPK, glucose regulation<\/td>\n<\/tr>\n<tr>\n<td>White Mulberry Leaf<\/td>\n<td>150 mg<\/td>\n<td>DNJ, flavonoids<\/td>\n<td>Reduced carbohydrate absorption<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><strong>Documented Effect According to the Literature<\/strong><\/p>\n<p>Based on human and preclinical studies of the ingredients:<\/p>\n<ul>\n<li><strong>Increased metabolic activity:<\/strong> ~5\u201310%<br \/>\n\u2022 <strong>Increased fat burning<\/strong> ~10\u201317%<br \/>\n\u2022 <strong>Action start time:<\/strong> 10\u201314 days of continuous use<br \/>\n\u2022 <strong>Further weight loss:<\/strong><br \/>\n\u2013 ~2\u20134 kg in 8\u201312 weeks<br \/>\n\u2013 mainly from fatty mass<br \/>\n(when combined with a mild calorie deficit)<\/li>\n<\/ul>\n<p><em>The effects vary depending on gender, age, diet, and physical activity.<\/em><\/p>\n<p><strong>Indications<\/strong><\/p>\n<ul>\n<li>Support for metabolism and thermogenesis<br \/>\n\u2022 Enhance fat tissue burning<br \/>\n\u2022 Blood sugar and appetite regulation<br \/>\n\u2022 Support for weight loss programs<br \/>\n\u2022 Daily caffeine-free use<\/li>\n<\/ul>\n<h2>The Scientific Literature of LOSEBiG THERMOGEN Ingredients<\/h2>\n<ol>\n<li><strong>Herranz-L\u00f3pez M, et al.<\/strong><br \/>\n<em>Lemon verbena and hibiscus polyphenol compounds help manage metabolic syndrome markers by activating AMPK.<\/em><br \/>\n2019;11(2):289.<br \/>\n\u2192 Documentation of AMPK activation, improvement of metabolic markers and fat mass (Metabolaid\u00ae).<\/li>\n<li><strong>Malag\u00f3n-Ruiz J, et al.<\/strong><br \/>\n<em>A botanical blend of Lippia citriodora and Hibiscus sabdariffa improves body composition in overweight subjects.<\/em><br \/>\n<strong>Applied Sciences.<\/strong> 2024;14(9):3882.<br \/>\nReduction of fat mass and body weight in 12 weeks without lifestyle changes.<\/li>\n<li><strong>Kondo T, et al.<\/strong><br \/>\n<em>Vinegar intake reduces body weight, body fat mass, and serum triglyceride levels in obese Japanese subjects.<\/em><br \/>\n<strong>Bioscience, Biotechnology, and Biochemistry.<\/strong> 2009;73(8):1837\u20131843.<br \/>\nDocumentation of the role of apple cider vinegar in weight and satiety management.<\/li>\n<li><strong>Hursel R, Westerterp-Plantenga MS.<\/strong><br \/>\n<em>Catechin- and caffeine-rich teas for the control of body weight in humans.<\/em><br \/>\n<strong>American Journal of Clinical Nutrition.<\/strong> 2013;98(6):1682S\u20131693S.<br \/>\nThermogenesis and increased fat oxidation through catechins (EGCG).<\/li>\n<li><strong>Dulloo AG, et al.<\/strong><br \/>\n<em>Efficacy of green tea extract rich in catechin polyphenols and caffeine in increasing energy expenditure.<\/em><br \/>\n<strong>American Journal of Clinical Nutrition.<\/strong> 1999;70(6):1040\u20131045.<br \/>\n\u2192 Increased energy expenditure and fat oxidation.<\/li>\n<li><strong>Zhang Y, et al.<\/strong><br \/>\n<em>Berberine activates AMPK and improves lipid metabolism.<\/em><br \/>\n2014;63(3):360\u2013368.<br \/>\n\u2192 AMPK pathway, lipid and glucose regulation.<\/li>\n<li><strong>Yin J, et al.<\/strong><br \/>\n<em>Efficacy of berberine in patients with metabolic disorders.<\/em><br \/>\n2008;57(5):712\u2013717.<br \/>\nClinical data for improving metabolic parameters.<\/li>\n<li><strong>Asano N, et al.<\/strong><br \/>\n<em>Mulberry leaf extract inhibits intestinal disaccharidase activity and suppresses postprandial hyperglycemia.<\/em><br \/>\n<strong>J Agric Food Chem.<\/strong> 2001;49(8):4208\u20134213.<br \/>\n\u2192 Reduced carbohydrate absorption, sugar control.<\/li>\n<li><strong>Yoneshiro T, et al.<\/strong><br \/>\n<em>Capsaicin and capsinoids increase energy expenditure by activating brown adipose tissue.<\/em><br \/>\n<strong>American Journal of Clinical Nutrition.<\/strong> 2012;95(4):845\u2013850.<br \/>\nThermogenesis and increased calorie burn through capsaicin.<\/li>\n<li><strong>Marreiro DN, et al.<\/strong><br \/>\n<em>Zinc and its role in energy metabolism and appetite regulation.<\/em><br \/>\n<strong>Biological Trace Element Research.<\/strong> 2017;179(2):1\u20139.<br \/>\n\u2192 Role of zinc in metabolic and hormonal balance.<\/li>\n<li><strong>K\u00fcllenberg D, et al.<\/strong><br \/>\n<em>Health effects of phospholipids in lipid metabolism.<\/em><br \/>\n<strong>Lipids in Health and Disease.<\/strong> 2012;11:3.<br \/>\nPhospholipids &amp; lipid metabolism (lecithin).<\/li>\n<\/ol>\n<p>&nbsp;<\/p>","protected":false},"excerpt":{"rendered":"<p>\u0394\u0399\u0391\u0398\u0395\u03a3\u0399\u039c\u039f \u0393\u0399\u0391 \u0391\u03a0\u039f\u03a3\u03a4\u039f\u039b\u0397 \u0391\u03a0\u039f 23 \u039c\u0391\u03a1\u03a4\u0399\u039f\u03a5 LOSEBiG THERMOGEN \u0397 \u0395\u03c0\u03b9\u03c3\u03c4\u03ae\u03bc\u03b7 \u03c4\u03b7\u03c2 \u039c\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ae\u03c2 \u0395\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7\u03c2 \u039f \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc\u03c2 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03bb\u03ce\u03c2 \u03b1\u03c1\u03b9\u03b8\u03bc\u03bf\u03af \u03b8\u03b5\u03c1\u03bc\u03af\u03b4\u03c9\u03bd.<\/p>","protected":false},"featured_media":6661,"comment_status":"closed","ping_status":"open","template":"","meta":{"_acf_changed":false},"product_brand":[1396],"product_cat":[1397,1399],"product_tag":[],"class_list":["post-6659","product","type-product","status-publish","has-post-thumbnail","product_brand-losebig","product_cat-1397","product_cat-ola-ta-proionta","first","onbackorder","sale","shipping-taxable","purchasable","product-type-simple"],"acf":[],"_links":{"self":[{"href":"https:\/\/amhes.com\/en\/wp-json\/wp\/v2\/product\/6659","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/amhes.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/amhes.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/amhes.com\/en\/wp-json\/wp\/v2\/comments?post=6659"}],"version-history":[{"count":1,"href":"https:\/\/amhes.com\/en\/wp-json\/wp\/v2\/product\/6659\/revisions"}],"predecessor-version":[{"id":6660,"href":"https:\/\/amhes.com\/en\/wp-json\/wp\/v2\/product\/6659\/revisions\/6660"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/amhes.com\/en\/wp-json\/wp\/v2\/media\/6661"}],"wp:attachment":[{"href":"https:\/\/amhes.com\/en\/wp-json\/wp\/v2\/media?parent=6659"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/amhes.com\/en\/wp-json\/wp\/v2\/product_brand?post=6659"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/amhes.com\/en\/wp-json\/wp\/v2\/product_cat?post=6659"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/amhes.com\/en\/wp-json\/wp\/v2\/product_tag?post=6659"}],"curies":[{"name":"wp.","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}